The Basic Principles Of ABBV-744
These findings are important for assessing the compound's usefulness in mitigating neurodegeneration.DNL343 is an investigational CNS-penetrant small molecule ISR inhibitor built to activate the eukaryotic initiation element 2B (eIF2B) and suppress aberrant ISR activation. DNL343 minimized CNS ISR exercise and neurodegeneration in the dose-dependen